PRED-462 could refer to a compound, a research project, or a specific study within the vast expanse of scientific inquiry. Without a specific context, one can only speculate on its nature; however, exploring possible areas of relevance can shed light on the kind of research that such a designation might be associated with.
PRED-462, or Prednisolone, is a widely used corticosteroid medication that provides effective relief for various inflammatory and autoimmune conditions. While it is generally well-tolerated, long-term use or high doses require careful monitoring to minimize side effects and risks.
PRED-462 High-Performance Computing Unit
| Property | Reported/Predicted Value | |----------|--------------------------| | | ~410 Da | | Core Scaffold | Substituted quinazolinone fused to a pyridine ring | | Key Functional Groups | Phenolic hydroxyl, tertiary amine, fluorinated aromatic ring | | Lipophilicity (cLogP) | 3.2 – 3.8 (moderately lipophilic, favoring oral absorption) | | Solubility | ~20 µM in pH 7.4 buffer (enhanced by formulation with cyclodextrin) | | Metabolic Stability | Low intrinsic clearance in human liver microsomes (t½ ≈ 45 min) | | Selectivity | >100‑fold selectivity for target X vs. off‑target kinases Y/Z (according to in‑vitro profiling) |
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Key elements to consider: